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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EGR2
All Species:
10.91
Human Site:
S458
Identified Species:
26.67
UniProt:
P11161
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11161
NP_000390.2
476
50302
S458
G
T
L
C
S
S
N
S
S
S
L
G
G
G
P
Chimpanzee
Pan troglodytes
XP_001165856
475
50152
S457
G
T
L
C
S
S
N
S
S
S
L
G
G
G
P
Rhesus Macaque
Macaca mulatta
XP_001092603
475
50169
S457
G
T
L
C
S
S
S
S
S
T
L
G
G
G
P
Dog
Lupus familis
XP_536361
472
49945
G454
G
P
L
C
S
S
N
G
S
T
I
G
G
G
S
Cat
Felis silvestris
Mouse
Mus musculus
P08152
470
49801
C451
S
Q
A
G
G
S
L
C
G
N
S
A
I
G
G
Rat
Rattus norvegicus
P51774
470
49831
C451
S
Q
A
G
G
S
L
C
G
N
S
A
I
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509408
291
31482
A274
A
A
A
A
A
A
A
A
A
A
A
A
G
P
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Q08427
421
46362
L404
R
D
R
Q
P
C
A
L
L
G
P
A
A
A
H
Zebra Danio
Brachydanio rerio
Q05159
412
45134
S395
S
S
S
S
T
G
V
S
S
S
E
R
G
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13360
604
62491
N581
N
N
S
S
N
G
S
N
G
A
T
G
V
G
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.1
96.2
N.A.
89
89.2
N.A.
39.7
N.A.
59.6
63
N.A.
21.5
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
99.5
97
N.A.
92.4
92.4
N.A.
45.7
N.A.
67.4
73.5
N.A.
35.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
66.6
N.A.
13.3
13.3
N.A.
6.6
N.A.
0
26.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
20
20
N.A.
40
N.A.
0
40
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
30
10
10
10
20
10
10
20
10
40
10
10
10
% A
% Cys:
0
0
0
40
0
10
0
20
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
40
0
0
20
20
20
0
10
30
10
0
50
60
70
30
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
20
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
40
0
0
0
20
10
10
0
30
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
0
0
10
0
30
10
0
20
0
0
0
0
0
% N
% Pro:
0
10
0
0
10
0
0
0
0
0
10
0
0
10
30
% P
% Gln:
0
20
0
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% R
% Ser:
30
10
20
20
40
60
20
40
50
30
20
0
0
0
10
% S
% Thr:
0
30
0
0
10
0
0
0
0
20
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _